Spaniards begin importing slaves from Africa to replace Indians who died from harsh working conditions and exposure to disease.
Twenty Africans are deposited at Jamestown, VA by a Dutch frigate.
Massachusetts is the first colony to legally recognize the institution of slavery.
The Maryland legislature enacts a law holding that conversion to Christianity does not alter ones slave status.
Virginia passes a law rewarding the killing of "Maroons", runaway slaves who maintain a nomadic existence on the western frontier. Between 1672 and 1864 dozens of "Maroon" communities are formed in the forest and swamps of South Carolina, Florida, Virginia, and other colonies and states.
Quakers in Germantown,PA denounce slavery in America's first recorded formal protest against the institution.